If Cenforce 150 mg doesn’t work the first time, don’t panic. Make sure you're taking it correctly—about 30 to 60 minutes before sexual activity and on an empty stomach, if possible. Fatty meals or alcohol can reduce its effectiveness. Sometimes, the body needs a few tries to respond to ED medication. If it doesn’t work after 3–4 separate attempts, it may be time to explore other options with your doctor. Avoid alcohol, recreational drugs, and certain medications that can interfere with how Cenforce 150 mg works. Also, ensure you are sexually stimulated, as the drug only works with arousal.